Mind and body approaches include meditation, spinal manipulation, massage, yoga, tai chi, hypnosis, and acupuncture. One of the first objectives we list in our new strategic plan is to advance understanding of the mechanisms through which mind and body approaches affect health, resiliency, and well-being. The work is challenging, but recent advances in genomic science, neuroscience, stem cell research, systems biology, neuroimaging, and predictive computational modeling offer excellent resources and opportunities for understanding how mind and body approaches may (or may not) perform their magic